The single-cell transcriptomic atlas iPain identifies senescence of nociceptors as a therapeutical target for chronic pain treatment

Abstract Chronic pain remains a significant medical challenge with complex underlying mechanisms, and an urgent need for new treatments.Our research built and utilized the iPain single-cell atlas to study chronic pain progression in dorsal root and Drinks trigeminal ganglia.We discovered that senescence of a small subset of pain-sensing neurons may

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TABAYYUN VALUES MANIFESTATION IN NAHDATUL ULAMA AND MUHAMMADIYAH IN ORGANISAZING THE INFORMATION AND COMMUNICATION IN JAMBI CITY

Abstract: This research is motivated by the rise of the phenomenon of negative news and hoaxes received by Nahdatul Ulama and Muhammadiyah.Hoax news is not without problems, destructive phenomena in society can be said to have started there, such as hate speech, discrimination, persecution, stereotypes and physical violence.However, the two Islamic

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